The project started in 1991 and it has successively received financial support from 12 projects sponsored by the KIB State Key Laboratory of Phytochemistry and Plant Resources in West China, Yunnan Natural Science Foundation and National Natural Science Foundation of China with total fund amounting to RMB 700,000 yuan. Plant cyclopeptide is a very important plant metabolite and also a new ...
In collaboration with State Key Laboratory of Medical Genomics in Shanghai Jiao Tong University, Shanghai Institutes for Biological Sciences in CAS, and Rui Jin Hospital, Prof. Sun Handong, academician of CAS, observed significant apoptosis of t (8; 21) chromosome translocation through NF-κB and MAPK pathways, concomitant with caspase-3 activation. AML1-ETO oncoprotein was degraded in pa...
The program has investigated 16 plants of the genus Schisandra and Kadsura. About 100 novel highly oxygenated rearranged triterpenoids and nortriterpenoids with new skeleton were discovered. Among them, several ones have been found to show significant anti-HIV bioactivity with minimal toxicity. This result has attracted much attention in the world. The researchers will continue to isolate ...
